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Neuroinflammation Neuroinflammation is increasingly recognized as a key factor interacting with neurobiological correlates of the neuropsychiatric long COVID syndrome, such as brain serotonin depletion [111], hypothalamic–pituitary–adrenal (HPA) axis dysregulation [57], and impaired hippocampal neurogenesis and plasticity [13, 61]

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10.1096/fj.03-0073rev 13 CallaghanR